Best Python backend options and SQLite integration

I’m working on a Python project and trying to figure out which backend framework would work best for my needs. There are so many options out there like Django, Flask, FastAPI and others that I’m getting confused about which one to pick.

Also, I keep hearing people mention SQLite as a good database choice for Python apps. What makes SQLite special compared to other databases? I’m curious about the specific benefits it offers and how exactly you would go about connecting it to a Python application.

Any recommendations or examples would be really helpful. I’m still learning so simple explanations would be great.

SQLite’s great because there’s no setup - everything lives in one file. Perfect for dev work and smaller apps. It runs inside your Python app instead of needing a separate server, so deployment’s way easier. For frameworks, pick based on what you’re building. Flask gives you total control and flexibility - use it when you want to decide how everything’s structured. Django’s the full package with admin panels, ORM, and auth built-in. Great for bigger projects where you want to move fast. FastAPI’s your best bet for high performance and auto-generated API docs. You can use Python’s built-in sqlite3 module for basic stuff, but I’d go with an ORM like SQLAlchemy. Better data modeling and your code stays cleaner. Works great with all three frameworks.

sqlite’s perfect for beginners - literally zero setup. just import sqlite3 and you’re done. no servers to configure like with postgres or mysql. for frameworks, django might be too much if you’re just learning. flask’s way more beginner-friendly with tons of tutorials out there. fastapi’s awesome but i’d save it for later once you’ve got the basics down.

what kind of stuff are you planning to do with your app? knowing that can really guide your choice of framework. also, how comfy are you with databases? if you think you’ll scale up, sqlite might not cut it for larger datasets. why did you pick python for your project?